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The regulation of neuronal glucose transporter, neuronal mitochondrial function, and insulin sensitivity in the brain mediates this effect

However, what's really causing the hair loss isn't as simple as a medication

For most individuals experiencing headaches whilst taking tirzepatide, symptoms are mild, transient, and manageable with conservative measures

While its primary functions target appetite control and blood sugar management, these effects can create secondary changes in fluid intake, kidney function, fluid balance, and saliva production

The GIP component enhances insulin secretion when blood glucose is elevated and may also influence fat metabolism, though its exact contribution to weight loss in humans is still being studied